GASTRIC CANCER TREATMENT IN SINGAPORE

Gastric Cancer Treatment in Singapore

Gastric Cancer Treatment in Singapore

Blog Article

Overview of Gastric Cancer


Gastric cancer, also known as stomach cancer, is a disease in which malignant cells form in the lining of the stomach. It is one of the most common cancers worldwide, particularly prevalent in East Asia. Although its incidence has declined in many developed countries due to better hygiene and food preservation, it remains a significant health concern. Early detection and appropriate Gastric cancer treatment in Singapore  are crucial for improving survival rates.

Singapore as a Medical Hub


Singapore is recognized globally as a leading medical hub in Asia. The country offers world-class healthcare services, advanced medical technologies, highly skilled healthcare professionals, and a well-regulated healthcare system. Patients from all over Southeast Asia and beyond seek cancer treatment in Singapore due to its high success rates and integrated care approach.

Diagnosis and Staging


Accurate diagnosis and staging are essential for effective treatment planning. In Singapore, patients can expect comprehensive diagnostic services, including:

  • Endoscopy with biopsy: To visually inspect the stomach and obtain tissue samples.

  • Endoscopic ultrasound (EUS): For assessing the depth of tumor invasion.

  • CT and PET scans: To detect spread to lymph nodes or distant organs.

  • Laparoscopy: Sometimes used for staging before surgery.

  • Histopathological and molecular testing: For identifying specific mutations or biomarkers that may guide targeted therapy.


Singaporean hospitals utilize state-of-the-art diagnostic tools to ensure precise staging, which directly influences treatment strategies.

Treatment Options in Singapore


Treatment for gastric cancer in Singapore follows evidence-based protocols, often aligned with international guidelines such as those from the NCCN or ESMO. Treatment typically depends on the cancer stage, location, patient’s general health, and preferences.

1. Surgical Treatment


Surgery is the mainstay of treatment for localized gastric cancer. The most common surgical procedures include:

  • Subtotal (partial) gastrectomy: Removal of the cancerous portion of the stomach.

  • Total gastrectomy: Removal of the entire stomach, often required for more extensive cancers.

  • Lymph node dissection: Essential to reduce the risk of recurrence.


Minimally invasive techniques such as laparoscopic or robotic-assisted surgery are increasingly being used in Singapore’s top hospitals, offering faster recovery and fewer complications.

2. Chemotherapy


Chemotherapy may be used:

  • Neoadjuvantly (before surgery) to shrink tumors

  • Adjuvantly (after surgery) to destroy residual cancer cells

  • As palliative therapy in advanced or metastatic stages


Common drugs include fluoropyrimidines (e.g., 5-FU, capecitabine), platinum agents (cisplatin, oxaliplatin), and taxanes.

3. Radiotherapy


Radiotherapy may be combined with chemotherapy (chemoradiation), especially in cases where surgery is not possible or to control local tumor growth. Singapore’s cancer centers offer highly precise radiation techniques like IMRT (Intensity-Modulated Radiation Therapy) to minimize side effects.

4. Targeted Therapy


For HER2-positive gastric cancers, trastuzumab (Herceptin) is a standard targeted therapy. Singapore hospitals have access to the latest HER2 testing and targeted agents.

Other newer agents like ramucirumab, nivolumab, and apatinib are considered based on molecular profiling and treatment goals.

5. Immunotherapy


Immunotherapy is an emerging option, particularly in advanced gastric cancer. Drugs like nivolumab and pembrolizumab, which inhibit PD-1/PD-L1 pathways, are being used in select patients based on biomarkers like MSI status or PD-L1 expression.

Leading Cancer Centers in Singapore


Some of the most reputable hospitals and cancer centers offering gastric cancer treatment include:

1. National Cancer Centre Singapore (NCCS)



  • A national and regional leader in cancer research, education, and treatment.

  • Offers multidisciplinary care involving oncologists, surgeons, radiologists, and palliative care teams.


2. Singapore General Hospital (SGH)



  • One of Singapore’s oldest and most comprehensive tertiary hospitals.

  • Home to experienced gastrointestinal cancer specialists.


3. National University Cancer Institute, Singapore (NCIS)



  • Located at the National University Hospital (NUH).

  • Provides advanced treatment and participates in cutting-edge research and clinical trials.


4. Mount Elizabeth Hospitals (Orchard and Novena)



  • Popular among medical tourists.

  • Offers premium care, personalized service, and access to top oncologists.


5. Parkway Cancer Centre



  • A private cancer care provider with a strong international patient base.

  • Known for personalized medicine and advanced treatment options.


Multidisciplinary Care Approach


Gastric cancer treatment in Singapore is typically delivered through a multidisciplinary team (MDT) approach, ensuring comprehensive patient management. The team may include:

  • Surgical oncologists

  • Medical oncologists

  • Radiation oncologists

  • Pathologists

  • Radiologists

  • Gastroenterologists

  • Oncology nurses

  • Dietitians

  • Psychologists and social workers


This coordinated care model enhances treatment outcomes and improves quality of life for patients.

Clinical Trials and Research


Singapore is at the forefront of clinical research in Asia. Institutions like NCCS and NCIS frequently conduct clinical trials on:

  • New chemotherapeutic agents

  • Immunotherapy combinations

  • Precision medicine approaches

  • Biomarker-driven treatments


Eligible patients may benefit from early access to innovative therapies that are not yet widely available.

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